17 June 2027 · Princeton, New Jersey

Drug Discovery Innovation Programme

One focused day of insight and connection — keynotes, case studies and partner slots.

One-Day Agenda

Sessions Partner Slots Breaks & Admin
Bright Start: Welcome Coffee, Registration & Itinerary Collection
Welcome Note from World BI
Chairperson Welcome Address
Opening Presentation

Closing the Human Biology Gap: Building More Predictive Preclinical Models

  • Improving the human relevance of preclinical models for better translation
  • Using organoids, human tissues, 3D models and advanced in vitro systems to capture disease biology
  • Identifying where current models fail and how next-generation approaches can improve prediction
Keynote Presentation

New Modalities, New Challenges: What Does It Take to Build a Clinically Viable Medicine?

  • Translating emerging modalities from scientific promise into viable therapeutic candidates
  • Addressing challenges in efficacy, selectivity, delivery, safety and manufacturability
  • Understanding what differentiates promising new modalities from clinically viable medicines
Partner Slot 1

TBC

Coffee Break & Networking Session
Presentation 1

AI in Drug Discovery: From Prediction to Experimental Validation

  • Applying AI and machine learning to target identification, molecular design and drug discovery decisions
  • Moving beyond computational predictions toward experimentally validated results
  • Integrating AI with biological data and laboratory workflows to improve discovery efficiency
Partner Slot 2

TBC

Deep Dive Session

The Lead Optimization Challenge: Balancing Potency, Selectivity, Exposure & Developability

  • Optimising potency and selectivity without compromising pharmacokinetic properties
  • Managing ADME, exposure and physicochemical liabilities during lead optimisation
  • Making better candidate-selection decisions through multiparameter optimisation
Partner Slot 3

TBC

Problem Solution Matrix

Predicting Human Safety Earlier: Why Preclinical Safety Signals Still Fail to Protect Clinical Programs

  • Understanding why preclinical safety findings do not always predict human outcomes
  • Improving early identification of toxicity and safety liabilities
  • Integrating translational models and safety data into earlier development decisions
Luncheon and Networking
Presentation 2

AI + Human Expertise: Where Should We Trust Algorithms—and Where Do Scientists Still Need to Lead?

  • Defining where AI can enhance scientific decision-making and where human judgement remains essential
  • Managing model uncertainty, bias and explainability in drug discovery
  • Building effective human–AI workflows that combine computational speed with scientific expertise
Partner Slot 4

TBC

Strategic Discussion

Crossing the Biotech Valley of Death: De-Risking Early Programs for the Next Investment Milestone

  • Identifying the scientific and development risks that prevent promising programmes from progressing
  • Building stronger evidence packages to reach the next funding or development milestone
  • Aligning scientific validation, development strategy and investor expectations to improve programme success
Coffee Break & Networking Session
Presentation 3

Target Validation in Complex Biology: From Biological Association to Therapeutic Confidence

  • Moving from genetic and biological associations to functional evidence of target relevance
  • Strengthening target validation across disease models and biological contexts
  • Improving confidence in target selection before major discovery investment
Partner Slot 5

TBC

Panel Discussion

Can We Make Drug Discovery Faster, Smarter & More Predictable?

  • Where current drug discovery workflows create unnecessary delays, cost and uncertainty
  • How better collaboration, data integration and decision-making can improve R&D productivity
  • What the industry needs to change to move promising programs forward with greater confidence
Chair Closing Remarks
Day 1 End

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